Association of infant feeding practices in the general population with infant growth and stool characteristics.

Han et al. 2011 (Seoul, South Korea)

Overview

This second clinical study provided additional data on the suitability of Whole Goat Milk Formula (WGMF) for infant growth and tolerance outcomes up to 12 months of age. It also investigated the relationship between infant feeding practices and detailed stool characteristics (a measure of gut health and tolerance). This study provided meaningful insights regarding the potential of WGMF as an alternative to Cow Milk Formula (CMF) in diverse feeding scenarios. The bowel motions and stool characteristics of infants consuming WGMF were more similar to those of breast-fed infants.

Methods

Principal Investigator: Professor Sang-Il Lee, Sungkyunkwan University, South Korea

Ethics approval: Samsung Medical Centre

Formulations: Commercially available Dairy Goat Co-operative Whole Goat Milk Formula (WGMF; 20:80 whey-to-casein ratio; more than 50% total fat from goat milk; no added whey) and commercially available Cow’s Milk Formula (CMF; Whey enhanced; none or negligible amount of milk fat).

This prospective cohort study was conducted in Seoul, South Korea, involving 976 full-term, healthy infants. Infants were retrospectively classified into five feeding groups based on their predominant diet during the first four months:

  • Breast Milk Only
  • WGMF Only
  • CMF Only
  • Breast Milk + WGMF Combination
  • Breast Milk + CMF Combination

During routine medical assessments, data on feeding type, infant growth (weight and height), and stool frequency/consistency were collected at birth, four months, eight months, and twelve months. Mothers categorised stool characteristics using analogue scales.

Key findings

The growth rates (weight and height) of infants receiving WGMF exclusively or combined with breast milk mirrored those of breastfed infants and those fed either a combination of breast milk and CMF or CMF only*.

Data on bowel motion frequency (3-7 per day) and consistency of stools (overall softer) were closer to those of breastfed infants.† CMF-fed infants had fewer bowel motions (1-4 per day) and harder stool consistency than breastfed infants.‡ Analysis was undertaken for infants up to 4 months of age to avoid the confounding effects of other foods being introduced.

Conclusion

This study contributed to the evidence that whole goat milk formula is safe and suitable for feeding infants in the first 12 months of life. It provided new findings that infants fed WGMF had similar bowel motions to those of breast-fed infants, suggesting that WGMF may provide better gastrointestinal outcomes than CMF.

References

The clinical studies referenced on this page were conducted using a goat milk–based infant formula manufactured by the Dairy Goat Co-operative (New Zealand). Nannycare goat milk formula is manufactured by the Dairy Goat Co-operative (New Zealand) and has a formulation closely equivalent to that used in these studies. This supports the scientific relevance of the clinical outcomes to the Nannycare formulation.”

ANOVA: analysis of variance; CMF: cow milk formula; WGMF: whole goat milk formula.

*All groups had similar growth outcomes to 12 months of age. P>;0.05 for weight and height up to 12 months.

† P>0.05 for number of bowel movements and stool consistency between 0 and 4 months. Only data between 0 and 4 months were analysed because introducing other foods would confound the effects of breast or formula feeding on gastrointestinal function beyond 4 months.

‡ CMF-fed infants were more likely to have only 1–2 bowel motions per day and less likely to have more than > 7 bowel motions per day than breastfed infants (P<0.05).

Han et al. Nutr Res Pract. 2011; 5(4):308-312

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Breastfeeding is best for babies. Introducing partial bottle feeding could negatively affect breastfeeding. Professional advice should be sought before using an infant formula. Good maternal nutrition is important for breastfeeding, and reversing a decision not to breastfeed can be difficult.

Proper use of an infant formula product is important to the health of the infant. Infant formulas should be used as directed.

All information on the following pages about infant formulas is provided for educational and informational purposes only.